How to Increase White Blood Cell with Food |Causes, Counts,

by Dr. Suzanne Holroyd

What are white blood cells?

Unlike red blood cells, white blood cells are not anucleate and are cellular components of blood. White blood cells don’t have hemoglobin. That’s why their color is not red; these can be transported to the infection site and protects the body against foreign antigens and pathogens. But when these infections can’t be appropriately cured, then what is the reason behind it?

It may be due to a drop in white blood cell count. Oh no! It’s an alarming situation for your defense system; even a minor attack of an antigen is harmful to a patient with the least number of white blood cells. The blood count is incomplete without a white blood cell count.

How to Increase White Blood Cell with Food

In the Below article complete detail about the how to increase white blood cell with food.

Different types of white blood cells

Components of the immune system

Components of the Immune system The immune system is vast enough as any country’s defense system. At various points checks posts have been built –up. Main weapons of this troop or components of the immunity are: 1. WBC (White Blood cell) 2. Antibodies 3. The Complement system 4. The lymphatic system 5. Spleen 6. Thymus 7. Bone Marrow To understand immunity and its components first of all we should know about four main types of pathogenic microbes. These are bacterias, pathogenic fungi, parasites, and viruses. Against specific pathogen adaptive immune response produces antibodies. An adaptive immune response is an eternal modification as an adaptation to infection with pathogenic microbes. Phagocytic cells e.g., macrophages digest these pathogenic microbes. These macrophages are instantly accessible to fight against these pathogens and are the main components of the innate immune system. Production of antibodies only possible after infection and specific antibodies are produced against a wide scale of antigens these antigens trigger the production of antibodies. Components of the immune system Responses of both the adaptive immune response and innate immunity depend upon the activities of WBC. Key components of the innate immunity are granulocytes and macrophages. The main components of the Adaptive immune system are lymphocytes that provide lifetime immunity. Adaptive and Innate Immune system both in collaboration builds up a powerful defense system. Due to these strong immune systems, in this world full of infectious microbes we become ill infrequently. Numerous inflammations can be overcome by innate immune systems and no disease occurs while other infections which can’t be determined by innate immune system it will stimulate adaptive immunity and then easily cured by remaining immunological memory. Leukocytes arbitrate immune response and these leukocytes are derived from progenitors or precursors in the bone marrow. Hematopoietic Stem Cells These stem cells induce production of lymphocytes and myeloid these lymphocytes are accountable for adaptive immunity and myeloid lineages have role in both innate and adaptive immunity. Granulocytes These include Neutrophils, eosinophil, and basophils and they are circulated in the blood act as effector cells at sites of inflammation. Macrophages and mast cells are involved in the differentiation of tissues and work as effector cells and stimulates inflammation. Macrophages engulf bacteria and Switch on other phagocytic cells which are neutrophils. Mast cells are responsible to arrange defense mechanisms against pathogenic parasites and stimulate allergic soreness and they further manage eosinophils and basophils which are exocytic. Immature phagocytes e.g., dendritic cells penetrate in tissues and start engulfing antigens. Then these dendritic cells with antigens go towards lymphoid tissues. Two types of lymphocytes • B lymphocytes: These become matured in the bone marrow. • T lymphocytes: Their maturation spot is present in the thymus. Bone marrow and thymus are primary lymphoid organs while mature lymphocytes recirculate in blood by secondary lymphoid organs through lymphatic vessels. When a recirculating T cell recognizes specific antigen on the surface of a dendritic cell it will stimulate the adaptive immune system. Secondary lymphoid tissues are of three types as spleen this spleen capture antigen from bloodstream then lymph nodes caught antigen from the spot of infection in the tissues and mucosal-associated lymphoid tissues (MALT) which collect antigen from epithelial surface of the body. Adaptive immune responses begin in these secondary lymphoid tissues in which T cells that meet with antigen then these T cells will multiply and change into antigen-specific effector cells and B cells will grow, multiply and transform into antibody-secreting cells. Now come back to the main discussion which is components of the immune system. It is clear to some extent that cells of the immune system mainly produced in the bone marrow where some become matured and then move from here to protect peripheral tissues by circulating in the bloodstream and through the lymphatic system The main weapons that are white blood originated from precursors in the bone marrow. Red blood cells that are responsible for the transport of oxygen, platelets that are involved in blood clotting at a damaged portion in the body, and WBCs are all obtained by hematopoietic cells or pluripotent hematopoietic stem cells which are precursor cells in the bone marrow. These stem cells produce different types of blood cells. Myeloid Progenitor The precursor of the granulocytes, macrophages, dendritic cells, and mast cells of the immune system is the myeloid progenitor. Macrophages Macrophages play important role in innate immunity. They are the mature shape of monocytes, these monocytes circulate in the blood and covert continuously into macrophages upon transportation into the tissues. Dendritic cells These cells catch an antigen and exposed it for identification by lymphatic cells. Migration of immature dendritic cells from blood to stay in tissues and then phagocytic and macro-pinocytosis start digesting a massive amount of fluid which is outside from the cells. When these cells came across a pathogen they quickly become mature and move towards lymph nodes. When these dendritic cells are attacked by pathogen these become mature enough and move towards lymph nodes. Mast Cells Precursors of mast cells are not well defined, however, these mast cells also differentiate in the tissues they stay near the blood vessels and after activation, these release their substances which affect vascular permeability. Mat cells have a role to plan and arrange allergic responses and protect mucosal surfaces against antigens. Granulocytes Granulocytes or polymorphnuclear leukocytes have granules in their cytoplasm. Three types of granulocytes are Neutrophils: Most important component of the immune system, its deficiency leads to increases in bacterial infections. Eosinophil: Eosinophils have role against parasitic infection. Basophils: Its function is same as eosinophils and mast cells. Lymphoid precursor This progenitor gives rise to the lymphocytes. Two types of lymphocytes B lymphocytes: When these are activated these are differentiated into plasma cells that secrete antibodies. T lymphocytes: There are two main classes of T cells, one class convert into cytotoxic T cells on activation which kill virally infected cells, while another class activates other cells like B cells and macrophages. Maturation of lymphocytes in bone marrow or Thymus Lymphoid organs are well-characterized tissues having plenty of lymphocytes with non-lymphoid cells. In lymphoid organs, there is an interaction between lymphocytes with non-lymphoid cells for development, initiation of adaptive immune responses, and long-lasting lymphocytes. Two main types of lymphoid organs: Central or primary lymphoid organs include bone marrow and thymus organ in the upper chest here lymphocytes are produced. Both B and T lymphocytes are generating in the bone marrow while just B lymphocytes become mature in the bone marrow. For maturation of T cells, these T cells go towards Thymus. B cells are known as B cells because these are derived from Bone marrow and T cells are derived from Thymus so their name is T cell because their origin is Thymus. After maturation of both types of lymphocytes both launched into the blood circulation and through bloodstream both move towards secondary or peripheral lymphoid organs. The next step of the defense system is that the peripheral or secondary lymphoid organs are ready to capture antigen and permit the inauguration of adaptive immune responses and provide signals to support recirculating lymphocytes. The antigen can move into the body in many ways and causes infection or inflammation anywhere but suddenly attacked by secondary or peripheral lymphoid organs i.e., the spleen, lymph nodes, and by mucosal lymphoid tissues. Lymphocytes are also recirculating in these tissues (spleen, lymph nodes, and mucosal lymphoid tissues) where the antigen is brought from the spot of infection. These antigens are initially present within macrophages and dendritic cells. After maturation of dendritic cells then these matured dendritic cells will expose antigen to lymphocytes. Lymph Nodes These are well-organized structures and their location is at the merging points of blood vessels or the lymphatic system which is a system of vessels for collection of extracellular fluid from tissues and again return it to the bloodstream. Lymph This extracellular fluid which is produced consistently by filtration from the blood is known as lymph. And the vessels are called lymphatic vessels. Location of spleen The spleen is a palm-sized organ behind the stomach which gathers antigen from the blood. It also accumulates and destroys old red blood cells. It’s the main spot of disposal of old red blood cells. Despite the different appearance of the lymph nodes, spleen, and mucosal-associated lymphoid tissues all work on the same rule i.e., capturing or trapping antigen from the point of infection and stimulating an adaptive immune response. The peripheral or secondary lymphoid tissues provide signals to the lymphocytes that do not attack by their particular antigen, so these lymphocytes continue to live and recirculate until they come across with their specific antigen. This process is necessary to sustain the correct numbers of circulating T and B lymphocytes and make sure that only potential lymphocytes for an antigenic response should survive. Lymphocytes circulate between blood and lymph. Small B and T lymphocytes that completed their maturation in the bone marrow and thymus but have not still attacked by antigen are known as naïve or natural lymphocytes. These cells circulate constantly from the blood into the peripheral or secondary lymphoid tissues, where they enter by compression between the cells of capillary walls. They are then returned to the blood through the lymphatic vessels or, in the case of the spleen, return directly to the blood. When any infection appears lymphocytes identify the infectious factor and then this lymphocyte is pick up by lymphoid tissues where it multiplies and convert into effector cells which are necessary to cope up with the infection. When a huge amount of antigens are absorbed by dendritic cells which move towards lymph nodes via afferent lymphatic vessels. In these lymph nodes, these dendritic cells expose antigen to T lymphocytes and these T lymphocytes will activate B cells which will capture antigens. After these antigen-specific lymphocytes will multiply and differentiated making lymph nodes as effector cells and peripheral lymphoid tissues will initiate an adaptive immune response. Diffused mucosal lymphoid tissues will emerge in response to infection and then vanished. And then they will appear as more organized during infection e.g., B cell follicles of the lymph nodes enlarged as B lymphocytes, multiply and the entire lymph node will be expanded this phenomenon is known as swollen glands. Principles of innate and adaptive immunity Front Line soldiers Macrophages and neutrophils of the innate immune system provide defense against many microbes and are important for the elimination of various common bacterial infections. However, they cannot always remove infectious agents and cannot identify some pathogenic agents. Second Line troop To cover up these front line soldier’s lymphocytes of the adaptive immune system jump into the battle and ensures more strong defense system and protect against reinfection with the identical and same pathogen. It takes 4-7 days to initiate adaptive immune response so in this duration, the innate immune system has a crucial role. Function of antibodies Antibodies deal with pathogens and their toxic products. These are the foremost products of adaptive immune response found in fluid elements of blood, plasma, and in extracellular fluids. Immunity stimulated by antibodies is known as humoral immunity. Antibodies bind to the pathogen and restrict their toxic products by obstructing their approach towards body cells. This process is known as neutralization which is important for protection against pathogenic toxins. Just binding of antibodies with pathogens is not enough to stop the replication of bacteria that proliferates from outside of the cells. In this way antibody allows a phagocytic cell to engulf and dispose of bacteria. This is necessary for many bacteria that are resistant to direct recognition by phagocytes instead the phagocytes identify the constant region of antibodies coating the bacterium. The covering of pathogens and foreign particles in this way is known as opsonization. The compliment System System of plasma protein is known as a complement system that is activated by antibodies or without the help of antibodies on many microbial surfaces which is helpful to innate as well as adaptive immunity. Pore formation by activation of complement substances directly smash bacteria and this process is necessary for some bacterial infections. However, the main purpose of the complement system is to coat antigens with antibodies and make engulfing possible by phagocytes to demolish bacteria’s which may remain unrecognized if not assisted with the complement system. Complement also increases the germicidal performance of phagocytes in other words it “Complements” the activities of antibodies. It's all about components of the immune system.

components of immune system

What Are The White Blood Cell Counts?

Average Normal Range Of WBCs – 3,500-10,500 white blood cells per µl of blood.

Low WBC Count – Less than 4,500 white blood cells per µl of blood.

High WBC Count – More than 11,000 white blood cells per µl of blood.

How White Blood Cells fight against diseases?

The primary function of white blood cells is to produce antibodies against any foreign antigen and ingest that foreign antigen and its cellular debris. These cells also kill cancerous cells along with infectious pathogens.

White blood cell count varies because of many reasons. An increase in the number of white blood cells occurs after exercise, while this number is decreased when you are at rest position. But it is dangerous when the number of WBCs drops abnormally.

 

Causes of the lower number of White Blood Cells

As production site of WBCs is mainly bone marrow inside the spongy tissues of some larger bones.

There may be different causes of decreased levels of White Blood Cells. These may be;

Viral infections

Sudden viral infections like flu may be the reason for the short-term decreased level of white blood cells.

Cancer

Cancer such as leukemia is another cause of leukopenia as it damages bone marrow.

Infectious diseases

Infectious diseases like HIV, AIDS, and tuberculosis may decrease white blood cells count to a dangerous level. According to a 2015 study, women suffering from tuberculosis are more prone to the least count of white blood cells than men.

Autoimmune disorders

 Lupus and rheumatoid arthritis are examples of autoimmune disorders that lead to leukopenia. 

Congenital disorders

 Also known as birth disorders such as Kostmann syndrome and myelokathexis causes leukopenia.

Malnourishment

 Lack of essential vitamins like B-12, folate, and minerals like copper and zinc is a major cause of a decreased number of white blood cells. 

Alcohol Consumption

Agree or not, but over-consumption of alcohol makes your immune system weak and decreases the number of white blood cells. 

 

Indicators of decreased WBCs Count

High fever

 When you have high degree fever, it is the main symptom of low white blood cell count that indicates your body’s organs are going through severe conditions because of decreased level of White Blood cells and are facing resistance to killing foreign pathogen; that’s why the temperature of machinery is increased because of more struggle with less equipment or white blood cells.

Chills and shivering

 You may feel seizures due to high fever, which also indicates the least white blood cell count.

Sweating

 As a result of high fever body response to maintain the temperature, and this can only be supported by sweating, so sweating indicates a high degree of temperature and lower white blood cells.

Swelling and redness

 Low WBCs count causes swollen lymph nodes and skin rashes, so these symptoms show a lower amount of white blood cells.

Mouth sores

 A lower level of WBCs or granulocytes may cause mouth ulcers, so if you are suffering from mouth soreness, it is a symbol of low WBC count.

A sore throat

Swollen glands and swollen lymph nodes are only because of problematic white blood cells because of White Blood cells’ lower level.

 

How least White Blood Cells count affect our body?

When you have a low white blood cell count, then your cancer therapy may be impeded.

In the case of AIDS, this condition is lethal for the individual.

Exposure to pathogenic infections will be more if you have a lower level of white blood cells.

What to do?

Resolve this problem as soon as possible; otherwise, this issue will attain more seriousness.

Eat right, enhance WBC count, and stay healthy. It takes about 1-2 weeks or more to raise the number of white blood cells.

How To Increase White Blood Cell Count Naturally

How to increase white blood cell count by food?

Almonds

Best dry fruits for weight loss

How to increase White Blood Cell with food

It is a gratuity by nature to fight against winter’s irritations like flu and cough. It contains vitamin E, which is obligatory for a strong immune system.

Lavender Essential Oil

The lavender essential oil has soothing effects, but it may be used as a booster for white blood cell count; thus, it is good enough to boost the immune system. Many other essential oils like cypress oil and sweet almond oils also can increase white blood cell count. 

Garlic

The pungent smell of garlic is sometimes unpleasant when we eat garlic in raw form, but when these are added into any dish, these enhance our appetite, and when a question arises, how to increase white blood cell count? Then take about 2-3 cloves of garlic and add it to every dish like curry, soup, macaroni, and garlic bread. Allicin in garlic will help produce white blood cells such as macrophages, lymphocytes, and eosinophils. Consume this magical bulb into your daily routine.

Spinach 

These super nutritious leaves have several types of vitamins, minerals, and antioxidants. These substances are necessary for the increment of white blood cells. You may add chicken and make a chicken soup with spinach. It will have a delicious taste ever, or you may add spinach to any salad.

Spinach is a rich source of vitamins and minerals. It also exhibits antioxidant properties (3). These properties can help in increasing the number of white blood cells.

Papaya Leaves

These leaves are mostly suggested during dengue fever because, in this fever, there is a very low amount of white blood cells, which is decreased to a dangerous level, so papaya leaves are a quick remedy to increase white blood cells because these contain acerogenins having properties to increase WBCs. Take a bunch of fresh papaya leaves, grind them, add some water for making juice, then blend this mixture, use a strainer to strain the liquid, and sip quick recovery. You may add honey to this mixture as these leaves are too bitter to consume. Drink it 1-2 times daily.

Vitamin E

Vitamin E is used in cosmetics to increase your beauty and glowing skin, but it also strengthens our immune system and triggers natural killer cells in the body. Production of B-cells can be enhanced by vitamin E intake, which increases the production of antibodies to kill off pathogens. Vitamin E supplements should be added to the diet of older people. Youngsters can get this vital vitamin from fruits, vegetables like spinach and broccoli, and seeds.  

Vitamin A

Smoky roasted liver of mutton or beef Slurp! Everyone wants to eat this mouthwatering item. What’s more, if this delicious dish also contains a high amount of vitamin A and this vitamin is necessary to increase white blood cells in the body. Our body can produce vitamin A by itself. Other vitamins A sources are fish, fortified cereals, carrots, mangoes and pumpkin.

 Carotenoids

Carotenoids mainly include β- carotene, which acts as an antioxidant to remove dangerous free radicals and increase white blood cell count.

 Green Tea

Green Tea eliminates toxins from the body and is also helpful during flu because it has polyphenols. Flavonoids and epigallocatechin gallate, or EGCG, are also present in green Tea, boosting the immune system and enhancing white blood cells. Amino acid L-thiamine present in green tea aid in producing germ-resistant compounds in the T-cells

 Turmeric

This should be the main ingredient if you are designing a diet plan to increase white blood cells because it is a great source of vitamin B6 and minerals, such as potassium, manganese, iron, and curcumin antioxidant that can boost up the immune system.

Flaxseed

Flaxseeds for diabetes

How to Increase White Blood Cell with Food

Flaxseeds are effective for diabetes  but are good for the immune system and increase the number of white blood cells in the body as they have alpha-linolenic acid, omega-3 fatty acids, and lignans.

Mushroom

Edible mushrooms are used for centuries to improve the immune system and increase white blood cell count, fighting against various infections.

 

 Vitamin B Complex

Vitamin B complex is a mixture of B6, B12, B3, B2, B5, B7 …B12 and is effective for the immunity system. So all these B vitamins should be added to increase the white blood cell count. Various sources of Vitamin B are eggs, milk, cheese, beans such as chickpeas, kidney beans, fish such as tuna, salmon, and mackerel, vegetables like potatoes, beets, and avocados, fruits such as watermelon, and banana and the list goes on.

 Yogurt

Yogurt should be added to our daily diet plan, but unfortunately, we skip this great dairy product. Yogurt purely contains probiotics, which is essential for a healthy immune system and is needed to increase the WBC. Just have a single small-sized bowl of yogurt, and it will be enough for the whole day but keep in mind that don’t eat it when your stomach is empty. 

Omega-3 Fatty Acids

Nowadays, with increased COVID -19, it became a headache for everyone on how to increase WBC? So you cannot overcome this problem only with the help of foods but also requires supplementation and specifically Omega-3 supplements that have immunomodulatory properties that improve the immune system by elevating WBCs. Omega-3 fatty acids increase the number of phagocytes, and these phagocytes are effective against pathogenic microbes and digest their debris. Add 1000 mg of omega-3 supplements after consulting with your doctor. You can get this polyunsaturated fatty acid from fish, like mackerel, sardines, salmon, and other foods, like walnuts and avocados, to increase your intake of omega-3s. Take this supplement only one time during a day.

Zinc

It would help if you increased the intake of zinc for a strong immune system and the proper functioning of WBCs. Zinc can be obtained from oysters, red meat, beans, and nuts, or you can use zinc supplements for quick results. Add 8-11 mg of zinc supplements to your daily routine until your recovery. Consult with your doctor for zinc supplementation.

Broccoli

This common vegetable must be included in your diet plan if you are suffering from low White blood cell count as it contains sulforaphane (SFN), which regulates functions of white blood cell count and boost up the immune system. You can consume it in your own way, either cooked or either as a salad.

Cauliflower

You may replace broccoli with white cauliflower. Both have a huge amount of antioxidants, such as glutathione, which helps the body produce resistance against viruses.

Citrus Fruits

It has now become a scientific truth that citrus fruits are made for the immune system. These are vital for improving the immune system’s proper functioning, so it can be denied that these are highly recommended fruits to increase white blood cell count. These include lemon, oranges, strawberries, and grapefruits, and the list goes on.

 Red Bell Peppers

These peppers not only increase the flavor of dishes but is a superb booster for the immune system. Include these peppers into your favorite dishes to get good results.

 Sunflower Seeds

These seeds are easily available and are less expensive, but these are full of various nutrients like phosphorus, magnesium, vitamin E, and vitamin B 6. These nutrients and antioxidants are present in these small seeds. That’s why these seeds are a very cheap package of these highly valued nutrients to keep your immune system strong and to upraise the white blood cell amount. You will need a handful of raw or salted sunflower seeds. You may sprinkle them on a salad or any other vegetable.

 

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